Symbol
Name
ID

Med1
mediator complex subunit 1
MGI:1100846

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal cardiovascular system morphology

abnormal blood vessel morphology

dilated liver sinusoidal space

abnormal placenta vasculature

abnormal placental labyrinth vasculature morphology

increased angiogenesis

abnormal vascular endothelial cell development

abnormal vena cava morphology

abnormal myocardial fiber morphology

decreased myocardial fiber mitochondrial DNA content

abnormal myocardial trabeculae morphology

trabecula carnea hypoplasia

myocardial trabeculae hypoplasia

thin myocardium compact layer

myocardium hypoplasia

thin myocardium

abnormal cardiovascular development

abnormal heart morphology

dilated heart atrium

enlarged heart

heart hypoplasia

ventricular hypoplasia

thin ventricular wall

dilated heart ventricle

pericardial effusion

cardiac interstitial fibrosis

dilated cardiomyopathy

abnormal cardiovascular system physiology

decreased cardiac muscle contractility

abnormal heart echocardiography feature

increased cardiomyocyte apoptosis

increased vascular permeability

congestive heart failure

Availability

Mouse Genotype

Med1^tm1.1Mpk/Med1^tm1.1Mpk

Med1^tm1Jkr/Med1^tm1Jkr

Med1^tm1Mpk/Med1^tm1Mpk

Med1^tm1Rgr/Med1^tm1Rgr

Med1^{tm3b(EUCOMM)Wtsi}/Med1⁺

Med1^tm2Jkr/Med1^tm2Jkr
Tg(Myh6-cre)2182Mds/0 (conditional)

Med1^tm2Jkr/Med1^tm2Jkr
A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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